What is the function of high frequency ventilation in patients with inhalation injury?

High-frequency ventilation (HFV) plays a significant role in patients with inhalation injury, particularly in the mobilization of secretions and soot from the lungs. Inhalation injuries often result in damage to the airway and pulmonary tissues due to thermal, chemical, or particulate matter exposure. This can lead to increased secretions and bronchial constriction.

HFV facilitates the clearance of these secretions by providing very small tidal volumes at a very high rate. This process helps in maintaining alveolar recruitment while minimizing the risk of barotrauma, as the pressure changes are more controlled. The rapid rate of ventilation allows for better clearance of mucus and soot, which is essential for improving lung function and oxygenation in injured patients.

In contrast, while HFV can have some effect on oxygenation due to improved ventilation-perfusion matching, its primary mechanism in the context of inhalation injury is the effective mobilization of secretions. Thus, it is crucial for lung hygiene, aiding in the prevention of secondary infections, and ultimately supporting recovery from lung injury.